When I go into 23andme's "Your Raw Data" section on the webpage, I can look up the results for a certain SNP. I used rs6565703. The data returned was:
Genes Marker (SNP) Genomic Position Variants Your Genotype DOC2B rs6565703 12344 A or C A / C
I understand that in order to get "Your Genotype" you must figure this out by what dosages are returned for each variant. However when I use the same user account, as seen above, the JSON file seems to be returning homozygous A(AA) as seen below.
Just trying to figure out, why these are different?
{
'accession_id' => 'NC_000017.10',
'is_no_call' => bless( do{\(my $o = 0)}, 'JSON::XS::Boolean' ),
'end' => 12344,
'alternate_ids' => [],
'variants' => [
{
'dosage' => '2',
'accession_id' => 'NC_000017.10',
'is_no_call' => $VAR1->[0]{'is_no_call'},
'end' => 12344,
'allele' => 'A',
'platform_labels' => [
'ILMN_CUSTOMv4',
'ILMN_OMNIEXv3_CUSTOMv3'
],
'is_assayed' => bless( do{\(my $o = 1)}, 'JSON::XS::Boolean' ),
'start' => 12343
},
{
'dosage' => '0',
'accession_id' => 'NC_000017.10',
'is_no_call' => $VAR1->[0]{'is_no_call'},
'end' => 12344,
'allele' => 'C',
'platform_labels' => [
'ILMN_CUSTOMv4',
'ILMN_OMNIEXv3_CUSTOMv3'
],
'is_assayed' => $VAR1->[0]{'variants'}[0]{'is_assayed'},
'start' => 12343
}
],
'id' => 'rs6565703',
'is_genotyped' => $VAR1->[0]{'variants'}[0]{'is_assayed'},
'is_assayed' => $VAR1->[0]{'variants'}[0]{'is_assayed'},
'gene_names' => [
'DOC2B'
],
'start' => 12343
}
So i was able to figure this out with some help from 23andme's support team. Turns out the issue was that an account can have multiple profiles. I was using the parent account ID instead of the child profile ID's which is why i was receiving differing results. You can use this endpoint to see if you have multiple profiles within the account.