I have this image...
I would like to transform it perspective like this via code...
Is that possible in MonoTouch?
Without having tried it, but as Monotouch sits on top of its ObjectiveC counterpart and binds almost all its API, I would say yes and therefore you may want to refer to this question here on Stackoverflow
and that one
How do I apply a perspective transform to a UIView?
They deal with almost the same effect you want to achieve. You should be able to translate the code into Monotouch pretty easily.
Happy coding.