I am seeing it in some download files e.g. OpenJDK21U-jdk_x64_linux_hotspot_2023-08-09-06-56.tar.gz
?
Some of the github brances are also suffixed with "U".
It means "update"
Based on the release guide for OpenJDK:
When the repository has been created, a few changes to the codebase will be necessary where the code references a jdk version but not it's new update version. I.e. jdk11 became jdk11u when it was moved to an update repository.