i've used this code to remove duplicates in column #3 from 2 files
awk -F, 'NR==FNR{seen[$3]; next} !($3 in seen)' dublicates.txt need_check.csv > output.csv
But how to check for duplicates if i want check multiply columns (#2,#3 and #4)?
Due to an ambiguity in your question, there are two possible answers.
If you consider as duplicates records that have the same fields #2, #3 AND #4, you should run:
awk -F, '{key=$2 FS $3 FS $4} NR==FNR{a[key]; next} !(key in a) dublicates.txt need_check.csv > output.csv
If records are duplicates when only one of the fields is repeated, then you have to code it in another way.
It is a good practice at SO to include a sample of input and the desired corresponding output.