Is there a way to automate the turning on or off of a Receive Location in BizTalk? It seems like there should be some kind of API or some such for this kind of thing. I would prefer to work in C#, but WMI or some kind of script would work too.
Besides ExplorerOM, as you've found out, you can also enable/disable receive locations (and control send ports) using WMI.
I have a sample PowerShell script that shows how to do those things here, if you're interested.