Is there any advantage or disadvantage to using .info domain names? They are certainly cheaper, but I'd like to know whether search engines or human users have known issues with them. For example, do search engines rank .com or .org lower than .info?
I am about to purchase forty or fifty domain names and I want some good info.
Any ideas or experience?
TLD has no effect on SEO except for local search. Since .info is a general TLD and not a country specific TLD using it will not have an impact on your rankings at all.