For example, when I want to make the leading value of 10 different UI elements match, should I be constraining 9 of them to the first item's leading value, or should I create a chain 1 -> 2 -> 3 -> 4 -> 5 -> 6 ...etc.
I was wondering about the performance differences and whether I should prefer one for maintenance reasons.
It's very difficult to answer an abstract question.
If you want the leading of 10 UI elements to match...
First, you're almost certainly better off putting them in a UIStackView
... you constrain the stack view's leading and you're done.
Second, if there is a reason you don't want to (or can't) use a stack view, then the answer depends on what else you might be doing.
Suppose you want element 3 "indented" 40-pts?
Suppose you want elements 5 through 10 "indented" 40-pts?
Suppose you want to "insert" an element between 3 and 4? Or remove element 6?
Suppose any of the above - or any number of other possibilities - are "conditional" and factor into the alignment?
As you can see, the preference of one over the other will depend on many things.