Given a program running on multiple cores, if two or more cores are operating on the same cache line, is there a way to measure the number of cache coherence invalidations/misses there are (i.e. when Core1 writes to the cache line, which then forces Core2 to refresh its copy of the cache line so that both cores are consistent)?
Let me know if I'm using the wrong terminology for this concept.
Yes, hardware performance counters can be used to do so.
However, the way to fetch them is use to be dependent of the operating system and your processor. On Linux, the perf too can be used to track performance counters (more especially perf stat -e COUNTER_NAME_1,COUNTER_NAME_2,etc.). Alternatively, on both Linux & Windows, Intel VTune can do this too.
The list of the hardware counters can be retrieved using perf list (or with PMU-Tools).
The kind of metric you want to measure looks like Request For Ownership (RFO) in the MESI cache-coherence protocol. Hopefully, most modern (x86_64) processors include hardware events to measure RFOs. On Intel Skylake processors, there are hardware events called l2_rqsts.all_rfo, and more precisely l2_rqsts.code_rd_hit and l2_rqsts.code_rd_miss to do this at the L2-cache level. Alternatively, there are many more-advanced RFO-related hardware events that can be used at the offcore level.