I'm working on a very demanding project (actually an interpreter), exclusively written in D, and I'm wondering what type of optimizations would generally be recommended. The project makes heavy use of GC, classes, asssociative arrays, and pretty much anything.
Regarding compilation, I've already experimented both with DMD and LDC flags and LDC with -flto=full -O3 -Os -boundscheck=off seems to be making a difference.
However, as rudimentary as this may sound, I would like you to suggest anything that comes to your mind that could help speed up the performance, related or not to the D language. (I'm sure I'm missing several things).
Compiler flags: I would add -mcpu=native if the program will be running on your machine. Not sure what effect -Os has in addition to -O3.
Profiling has been mentioned in comments. Personally under Linux I have a script which dumps a process's stack trace and I do that a few times to get an idea of where it's getting hung up on.
Not sure what you mean by GS.
Since you mentioned classes: in D, methods are virtual by default; virtual methods add indirections and are not inlineable. Make sure only those methods that must be virtual are. See if you can rewrite your program using a form of polymorphism that doesn't involve indirections, such as using template metaprogramming.
Since you mentioned associative arrays: these make heavy use of the GC; to speed them up, switch to a third-party library that works on top of std.allocator, such as https://github.com/dlang-community/containers
If some parts of your code are parallelizable, std.parallelism is a good tool for this.
Since you mentioned that the project is an interpreter: there are many avenues for optimizing them, up to JIT/AOT compilation. Perhaps you could link to an existing library such as LLVM or libjit.