Even tho the website is behind CloudFlare CDN, we decided to use OPCache to reduce the load on server as there are a maximum (peak) of ~400 active users per second (most of the time it's 50-100 u/s).
But most pages have some different data for each user, for example user's dashboard overview, most of the data is same but it has some different numbers for each user that needs to be up to date.
P.S. The website is running on PHP 7.3.4
opcache.memory_consumption
TLDR: Production code should always have OPCached enabled.