Since Python Serpent Compiler is considered outdated and not secure by Vitalik (also confirmed by this audit and here), it is more recommended to write/deploy Ethereum smart-contract from python with Vyper compiler.
It is sure that Vyper works on the Ethereum decentralized platform, but I would to know if Vyper is also compatible to deploy smart contract on the Ethereum Classic decentralized platform ?
If yes, how to setup Vyper for this use case ?
If no, what is the new python supported compiler to deploy smart contract on Ethereum Classic ?
To the best of my knowledge, both ETC and ETH use EVM for their code, and neither have diverged in their implementation of the EVM. This means that no extra setup should be necessary to get Vyper code running on ETC instead of ETH.