I am considering to use python serving json based web services, my priorities are, in order:
Apache->AJP->Flup->Python seems ok to me, would you recommend another setup or is this ok ?
What would AJP do in that setup? The only "flup" I can find is a package with a "Random assortment of WSGI servers", which doesn't seem very helpful.
I'd recommend you to look at Pyramid and Django. Two Python web frameworks with different philosophies that both fulfill your requirements. Then pick the one that you like best.