I would like to simulate an Amazon kindle in a VM.
Is there a way to simulate a Kindle on my computer, so I can see how my created books would look on a Kindle?
Assuming you're talking about the e-ink Kindles, Amazon Previewer (available for both Windows on Mac) will do what you want. Here's a list of its features, and there are more FAQs on the site.
* Highlights of Kindle Previewer functionality
* Ability to preview your content across Kindle devices and apps
* Support for previewing Kindle Text Pop Ups and Kindle Panel Views
* Accurate rendering of your content across Kindle devices and apps
* Faster previewing through features like Auto flip mode, Image flip mode
* Auto updates for future enhancements