I want to run this DOS command in C#, without executing a DOS command.
REG DELETE HKLM\SOFTWARE\Wow6432Node\WindowsApplication1\Status /f
Here's one approach. Note that you have to pass true to OpenSubKey in order to get Write permission.
var hklm = Microsoft.Win32.Registry.LocalMachine;
var subkey = hklm.OpenSubKey("Software\\Wow6432Node\\WindowsApplication1", true);
subkey.DeleteSubKey("Status");