My Windows 2008 R2 server with IIS7.5, for some reason when i try to download an xls file from the website, it gives me a 503 Service unavailable error. The mime-type is set properly for this website and I also tried adjusting the maxAllowedContentLength as well without success.
Apparently SQL Reporting Services (which wasnt even running) hijacks the /reports directory for every website. I had to open the Reporting Services admin and change the directory it uses.