I'd like to use the Wiimote (accelerometers, gyroscopes, infrared camera, etc, etc, etc) on various applications.
It's a bluetooth device, and I know others have connected it to their computer.
-Adam
Have you seen Johnny Chung Lee's 'Procrastineering' Blog? He's written a lot on the subject of using wii remotes and has some fantastic demonstration videos. [Edit] I just found out Mr Lee did a TED talk which gives a good introduction to the stuff he's done too...
There's a wealth of information over on Wiibrew.org - check out their Wiimote Library page for some other APIs if you want to look beyond c#. As an avid Python fan, I'm quite curious to have a play with the pyWiimote library :-)