I am currently developing a web application focusing primarily on Chrome 24.01312.57 and IE10. In the former browser, I am experiencing a large amount of lag. However, the latter experiences little to no lag, which is quite opposite to what everyone claims.
To show you the difference, I am recording the screens of my netbook using an iPhone while scrolling down The Chrome Webstore - something Google itself created.
Testing Equipment
Results
Note: Look at the mouse cursor and the scroll thumb - on IE10, the mouse is always on the the thumb whereas Chrome, it is all over the place indicating a high latency between mouse movement and the actual rendering.
Bottom Line:
Before I conclude, do realize that these lags on Google Chrome are increasingly magnified as the website becomes more complex and/or the specs go lower. However, IE10 is pushing the FPS quite high even in these conditions. I also did some analysis of the Chrome timeline. In reveals that the FPS drops as you zoom out to the point where rendering takes up to ~900ms per frame (on the Google Webstore) while IE10 is still fluid smooth (and better yet it retains that smoothness on an atom netbook)
PS: Bug Report: http://code.google.com/p/chromium/issues/detail?id=163092 but no recent developments on this currently.
Chrome struggles with painting, especially at high resolutions such as 2560x1440 and above. Many websites such as the Chrome Web Store, Facebook, etc. exhibit significant scroll lag on it. IE10 maintains 120 fps on my monitor while scrolling on these sites.