If I am building an application with backbone.js, what is the best tool or combo of tools to use for data persistence?
So I cannot answer my own question for another seven hours so I am throwing the answer in here:
I just found a great link to answer my own question. Exactly what I am looking for: http://pixelhandler.com/blog/2012/02/09/develop-a-restful-api-using-node-js-with-express-and-mongoose/
If you want something even simpler without the Mongoose dependency I've made a very short example on how to achieve basic persistence with Backbone, Express.js and MongoDB.